Genome Dynamics and Stability: Recombination and Meiosis : Models, Means, and Evolution 3 (2008, Hardcover) by book DOC, FB2, PDF
9783540689836 3540689834 "This book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated."--BOOK JACKET., In dreams, anything is possible. It can be an escape from a tortured reality, no matter how ephemeral that may be, or it can be a horror that you can't run from.A man who calls himself The Magistrate has created a dream world more encompassing than any virtual reality, through unseen hands in an unseen corporation. He preaches transcendence through dreams, another level of human evolution that separates the mind from the body entirely.His zealotry has swept up multiple dreamers into his project, from drug addicts to assassins to innocent children. The Metropolis, the first dream, is a city whose shape and influence are manipulated and altered by the dreamers inside; at times, it's a nightmare, but also believable enough that reality itself becomes a memory.The city kills those who try to push and expand its boundaries, for its dreaming existence is both limitless and constricted.For Ash, a dying man spending his final moments in the Metropolis, dreaming forever doesn't sound so appealing., Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated."
9783540689836 3540689834 "This book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated."--BOOK JACKET., In dreams, anything is possible. It can be an escape from a tortured reality, no matter how ephemeral that may be, or it can be a horror that you can't run from.A man who calls himself The Magistrate has created a dream world more encompassing than any virtual reality, through unseen hands in an unseen corporation. He preaches transcendence through dreams, another level of human evolution that separates the mind from the body entirely.His zealotry has swept up multiple dreamers into his project, from drug addicts to assassins to innocent children. The Metropolis, the first dream, is a city whose shape and influence are manipulated and altered by the dreamers inside; at times, it's a nightmare, but also believable enough that reality itself becomes a memory.The city kills those who try to push and expand its boundaries, for its dreaming existence is both limitless and constricted.For Ash, a dying man spending his final moments in the Metropolis, dreaming forever doesn't sound so appealing., Once per life cycle, mitotic nuclear divisions are replaced by meiosis I and II reducing chromosome number from the diploid level to a haploid genome and recombining chromosome arms by crossing-over. In animals, all this happens during formation of eggs and sperm in yeasts before spore formation. The mechanisms of reciprocal exchange at crossover/chiasma sites are central to mainstream meiosis. To initiate the meiotic exchange of DNA, surgical cuts are made as a form of calculated damage that subsequently is repaired by homologous recombination. These key events are accompanied by ancillary provisions at the level of chromatin organization, sister chromatid cohesion and differential centromere connectivity. Great progress has been made in recent years in our understanding of these mechanisms. Questions still open primarily concern the placement of and mutual coordination between neighboring crossover events. Of overlapping significance, this book features two comprehensive treatises of enzymes involved in meiotic recombination, as well as the historical conceptualization of meiotic phenomena from genetical experiments. More specifically, these mechanisms are addressed in yeasts as unicellular model eukaryotes. Furthermore, evolutionary subjects related to meiosis are treated."